Arrestins expressed in killifish photoreceptor cells
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چکیده
منابع مشابه
A second opsin gene expressed in the ultraviolet-sensitive R7 photoreceptor cells of Drosophila melanogaster.
We have identified a second Drosophila opsin gene, Rh4, which is expressed specifically in the ultraviolet-sensitive R7 photoreceptor cells. The two R7 opsins, Rh3 and Rh4, are expressed in nonoverlapping subsets of R7 cells. The Rh4 opsin shares 72% amino acid identity with Rh3, but is only about 35% homologous with the other 2 Drosophila opsins, ninaE and Rh2. Twenty-eight amino acids are con...
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PURPOSE To evaluate the abilities of recombinant adenovirus carrying the basic fibroblast growth factor (bFGF) gene to (1) produce bFGF protein in vitro and (2) rescue retinal photoreceptors in Royal College of Surgeons (RCS) rats in vivo. METHODS Cultured human retinal pigment epithelial cells were infected with one of the following two replication-deficient adenoviral vectors that drive ins...
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Introduction: Degenerative retinal diseases are main cause of irreversible blindness. Stem cells therapy is a promising way in these diseases. Therefore, mesenchymal stem cells because of its safety can produce degenerated cells and can play important role in treatment. The aim of this study was to examine morphological changes in injured retinal pigment epithelium (RPE) and photoreceptor cells...
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■ Abstract Visual transduction captures widespread interest because its G-protein signaling motif recurs throughout nature yet is uniquely accessible for study in the photoreceptor cells. The light-activated currents generated at the photoreceptor outer segment provide an easily observed real-time measure of the output of the signaling cascade, and the ease of obtaining pure samples of outer se...
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In the context of host-pathogen interaction, host cell receptors and signaling pathways are essential for both invading pathogens, which exploit them for their own profit, and the defending organism, which activates early mechanism of defense, known as innate immunity, to block the aggression. Because of their central role as scaffolding proteins downstream of activated receptors, β-arrestins a...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1997
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(97)00640-6